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These therapies use immune cells called T cells, genetically engineered with what are called chimeric Obesity disease predictions improved with metabolic information, study finds Bradley J. Fikes Body Mass Index, or BMI is commonly used to determine obesity, and the risk of obesity-related diseases such as heart disease and diabetes. However, people of normal weight may get these diseases, while some technically obese people may not.
That disease risk is more accurately predicted by adding Fikes The first step in testing an entirely new kind of HIV vaccine began this week, using a vaccine candidate designed at an antibody center located at Scripps Research in La Jolla.
Cell therapy, now artisanal and costly, heads for mass production Bradley J. Fikes Not so long ago, manipulating living cells to serve as therapies was a difficult and mysterious art.
Only a few biomedical companies and academic labs could claim proficiency. But in recent years, there's been an explosion of knowledge about how cells work, how they can become diseased and how The purchase offer comes after multiple signals that the local company was struggling More Biotech Wave of effective — and expensive — cell and gene therapies challenges health insurers Bradley J.
Fikes Cancer patients, family and friends cheered when the first immune cell therapy for cancer, Kymriah, was approved last year for difficult blood malignancies.
But the price of hundreds of thousands of dollars brought gasps. And as many other cellular and gene therapies head for approval, the wave Arnold, who joined the Illumina board in , is sharing the prize with American George P. As stem cell and gene technologies advance, La Jolla conference mushrooms Bradley J.
Fikes In , a few hundred mostly local researchers gathered in La Jolla to discuss the emerging but still science-fictiony field of stem cells. Since then, stem cells, enhanced by gene therapy, have progressed to yield breakthrough treatments, most spectacularly in cancer.
Privately held VelosBio is developing drugs Heart stents from Reva Medical do their job, then leave Bradley J. Fikes Coronary stents, those tiny mesh tubes that prop open blocked blood vessels, have helped millions of people avoid invasive and complicated bypass surgery.
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Food and Drug Administration said Thursday. The main business in San Marcos in the 19th and early 20th centuries was farming. In the midth century, dairies and poultry production became a big part of the business in the town.
San Marcos experienced a period of growth from onward, when the first water from the Colorado River arrived. Several small businesses were founded and the population rapidly increased to 2, San Marcos became an incorporated city on January 28, In the s, San Marcos was flourishing as the third fastest-growing city in the state, and had a population of 17, by The population continued to boom over the next two decades, surpassing 30, in and nearing 85, by According to the United States Census Bureau , the city has a total area of Due to the moderating influence of the nearby Pacific, temperatures rarely fall below freezing in winter and above degrees F.
July through September are usually the warmest months, although hot and dry Santa Ana winds can strike any month most common Autumn and raise risks of wildfires. Most of the rain falls between November and March, averaging about 13 inches per year, with up to 20 inches falling in the San Marcos Hills.
According to the City's Comprehensive Annual Financial Report,  the top employers in the city are:. The San Marcos Unified School District is one of the largest school districts in San Diego County and includes 20 schools with diverse educational programs for kindergarten through adult education students.
High Tech High, which started with a single school in , uses small-school settings, where students learn through projects, internships and interaction with professionals.
The main acre 0. It is a public two-year community college and is a member of the California Community Colleges system. It enrolls approximately 30, full-time and part-time students. A giant letter P for "Palomar" on the hillside above the campus is a ubiquitous landmark for San Marcos, visible miles away.
It was founded in and built on a acre 1. It enrolls about 14, students and offers 44 undergraduate programs, 10 graduate programs and 1 Doctorate in Education in three colleges and one nursing school. The University of St. The university's mission is the professional development of health care providers through innovative and individualized education.
They offer a unique, hands-on curriculum which provides students with the tools it takes to become skilled clinicians. San Marcos uses a council-manager system of government with a separately elected mayor. The city council consists of the mayor and four other members, who are elected at-large to alternating four-year terms. As of March , the city manager is Jack Griffin. The population density was 3, The racial makeup of San Marcos was 53, Hispanic or Latino of any race were 30, persons The Census reported that 82, people There were 27, households, out of which 11, There were 1, 5.
The average household size was 3. There were 19, families The population was spread out with 23, people The median age was For every females, there were Voice of San Diego is a non-profit online news outlet covering government, politics, education, neighborhoods, and the arts.
The San Diego Daily Transcript is a business-oriented online newspaper. San Diego led U. San Diego has an Due to the ratio of U. Scripps Company owns KGTV and KZSD-LP, they are not considered a duopoly under the FCC's legal definition as common ownership between full-power and low-power television stations in the same market is permitted regardless to the number of stations licensed to the area.
San Diego's television market is limited to only San Diego county. The Imperial Valley has its own market which also extends into western Arizona , while neighboring Orange and Riverside counties are part of the Los Angeles market.
Sometimes in the past, a missing network affiliate in the Imperial Valley would be available on cable TV from San Diego. In the midth century the city had mercury vapor street lamps. In , the city decided to replace them with more efficient sodium vapor lamps. In , San Diego announced plans to become the first U.
With the automobile being the primary means of transportation for over 80 percent of residents, San Diego is served by a network of freeways and highways. The stretch of SR that passes through Balboa Park is San Diego's oldest freeway, and has been called one of America's most beautiful parkways.
San Diego's roadway system provides an extensive network of cycle routes. Its dry and mild climate makes cycling a convenient year-round option; however, the city's hilly terrain and long average trip distances make cycling less practicable. Older and denser neighborhoods around the downtown tend to be oriented to utility cycling.
This is partly because of the grid street patterns now absent in newer developments farther from the urban core, where suburban style arterial roads are much more common. As a result, a majority of cycling is recreational. In , San Diego was rated the best city with a population over 1 million for cycling in the U. San Diego transit information about public transportation and commuting is available on the Web and by dialing "" from any phone in the area.
The city has two major commercial airports within or near its city limits. Tijuana International Airport has a terminal within the city limits in the Otay Mesa district connected to the rest of the airport in Tijuana , Mexico via the Cross Border Xpress cross-border footbridge.
It is the primary airport for flights to the rest of Mexico, and offers connections via Mexico City to the rest of Latin America. Recent regional transportation projects have sought to mitigate congestion, including improvements to local freeways, expansion of San Diego Airport, and doubling the capacity of the cruise ship terminal.
Freeway projects included expansion of Interstates 5 and around "The Merge" where these two freeways meet, as well as expansion of Interstate 15 through North County, which includes new high-occupancy-vehicle HOV "managed lanes". According to an assessment in , 37 percent of city streets were in acceptable condition. Airport projects include expansion of Terminal Two. San Diego has 17 sister cities, as designated by Sister Cities International: From Wikipedia, the free encyclopedia.
Redirected from San Diego, California. This article is about the city in California. For other uses, see San Diego disambiguation. For the historical train, see San Diegan train.
City in California, United States. Images from top, left to right: List of communities and neighborhoods of San Diego. List of tallest buildings in San Diego. Downtown San Diego skyline at day and night. View from Coronado in November Climate of San Diego.
Economy of San Diego. List of companies headquartered in San Diego. Culture of San Diego. Sports in San Diego. Primary and secondary schools in San Diego. Media in San Diego. List of people from San Diego. For more information on data coverage, see ThreadEx. Archived from the original Word on November 3, Retrieved August 25, City of San Diego. Retrieved November 5, The City of San Diego.
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Archived from the original on June 14, Retrieved February 17, The History of San Diego: The Saint and the City". Timeline of San Diego history".
Retrieved May 4, Archived from the original on July 21, Archived from the original on An Interpretive History Second ed. The Journal of San Diego History.
Office of the City Clerk. Retrieved May 27, A Foundation to Build on". Retrieved April 8, California State Military Museum. Archived from the original on July 14, Retrieved November 26, Retrieved September 22, Population History of Western U. Nazi Doctors, Human Experimentation, and Typhus , , p. Plague as Biological Weapons Agent". Retrieved December 21, San Diego History Center. Retrieved September 1, San Diego Union Tribune. The Limits of Public—Private Partnerships". Archived from the original on July 24, Retrieved November 4, Retrieved July 13, Archived from the original PDF on June 20, Retrieved July 20, Afoot and Afield in San Diego.
Wilderness Press, Berkeley, Calif. Fireman and Manuel P. San Diego has 9th best parks among survey of 50 U. Retrieved May 31, Retrieved May 16, Archived from the original PDF on June 30, San Diego Business Journal.
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An Introduction to the Region , by Philip R. Sunbelt Publications, San Diego. McKinsey November 2, Archived from the original on January 16, San Diego Natural History Museum. Archived from the original on October 25, Retrieved April 13, Corpus Christi Convention and Visitors Bureau. Archived from the original on December 27, Retrieved December 15, Retrieved April 27, Archived from the original on August 28, The named reference census was invoked but never defined see the help page.
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